Cargando…

ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics

BACKGROUND: Thiamine (vitamin B1) deficiency (TD) causes mild impairment of oxidative metabolism and region-selective neuronal loss in the central nervous system (CNS). TD in animals has been used to model aging-associated neurodegeneration in the brain. The mechanisms of TD-induced neuron death are...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Shuchen, Yang, Guang, Yong, Yue, Liu, Ying, Zhao, Liyun, Xu, Jing, Zhang, Xiaomin, Wan, Yanjie, Feng, Chun, Fan, Zhiqin, Liu, Yong, Luo, Jia, Ke, Zun-Ji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006372/
https://www.ncbi.nlm.nih.gov/pubmed/21110885
http://dx.doi.org/10.1186/1750-1326-5-54