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ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics
BACKGROUND: Thiamine (vitamin B1) deficiency (TD) causes mild impairment of oxidative metabolism and region-selective neuronal loss in the central nervous system (CNS). TD in animals has been used to model aging-associated neurodegeneration in the brain. The mechanisms of TD-induced neuron death are...
Autores principales: | Lee, Shuchen, Yang, Guang, Yong, Yue, Liu, Ying, Zhao, Liyun, Xu, Jing, Zhang, Xiaomin, Wan, Yanjie, Feng, Chun, Fan, Zhiqin, Liu, Yong, Luo, Jia, Ke, Zun-Ji |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006372/ https://www.ncbi.nlm.nih.gov/pubmed/21110885 http://dx.doi.org/10.1186/1750-1326-5-54 |
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