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Visualization of Gli Activity in Craniofacial Tissues of Hedgehog-Pathway Reporter Transgenic Zebrafish

BACKGROUND: The Hedgehog (Hh)-signaling pathway plays a crucial role in the development and maintenance of multiple vertebrate and invertebrate organ systems. Gli transcription factors are regulated by Hh-signaling and act as downstream effectors of the pathway to activate Hh-target genes. Understan...

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Detalles Bibliográficos
Autores principales: Schwend, Tyler, Loucks, Evyn J., Ahlgren, Sara C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006388/
https://www.ncbi.nlm.nih.gov/pubmed/21203590
http://dx.doi.org/10.1371/journal.pone.0014396