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Redox-Sensitivity and Site-Specificity of S- and N- Denitrosation in Proteins

BACKGROUND: S-nitrosation – the formation of S-nitrosothiols (RSNOs) at cysteine residues in proteins – is a posttranslational modification involved in signal transduction and nitric oxide (NO) transport. Recent studies would also suggest the formation of N-nitrosamines (RNNOs) in proteins in vivo,...

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Detalles Bibliográficos
Autores principales: Jourd'heuil, Frances L., Lowery, Anthony M., Melton, Elaina M., Mnaimneh, Sanie, Bryan, Nathan S., Fernandez, Bernadette O., Park, Joo-Ho, Ha, Chung-Eun, Bhagavan, Nadhipuram V., Feelisch, Martin, Jourd'heuil, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006389/
https://www.ncbi.nlm.nih.gov/pubmed/21203591
http://dx.doi.org/10.1371/journal.pone.0014400