RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila

Human immune cells penetrate an endothelial barrier during their beneficial pursuit of infection and their destructive infiltration in autoimmune diseases. This transmigration requires Rap1 GTPase to activate Integrin affinity1. We define a new model system for this process by demonstrating with liv...

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Detalles Bibliográficos
Autores principales: Siekhaus, Daria, Haesemeyer, Martin, Moffitt, Olivia, Lehmann, Ruth
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006444/
https://www.ncbi.nlm.nih.gov/pubmed/20495554
http://dx.doi.org/10.1038/ncb2063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006444/
https://www.ncbi.nlm.nih.gov/pubmed/20495554
http://dx.doi.org/10.1038/ncb2063

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