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RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila
Human immune cells penetrate an endothelial barrier during their beneficial pursuit of infection and their destructive infiltration in autoimmune diseases. This transmigration requires Rap1 GTPase to activate Integrin affinity1. We define a new model system for this process by demonstrating with liv...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006444/ https://www.ncbi.nlm.nih.gov/pubmed/20495554 http://dx.doi.org/10.1038/ncb2063 |