Mechanism for Multiple Ligand Recognition by the Human Transferrin Receptor

Transferrin receptor 1 (TfR) plays a critical role in cellular iron import for most higher organisms. Cell surface TfR binds to circulating iron-loaded transferrin (Fe-Tf) and transports it to acidic endosomes, where low pH promotes iron to dissociate from transferrin (Tf) in a TfR-assisted process....

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Detalles Bibliográficos
Autores principales: Giannetti, Anthony M, Snow, Peter M, Zak, Olga, Björkman, Pamela J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300677/
https://www.ncbi.nlm.nih.gov/pubmed/14691533
http://dx.doi.org/10.1371/journal.pbio.0000051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300677/
https://www.ncbi.nlm.nih.gov/pubmed/14691533
http://dx.doi.org/10.1371/journal.pbio.0000051

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