The inhibition of Bid expression by Akt leads to resistance to TRAIL-induced apoptosis in ovarian cancer cells

Epithelial ovarian cancer (EOC) cells often show increased activity of the PI3K/Akt pathway. In addition, we have previously shown that EOC ascites induce Akt activation in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-sensitive EOC cell line, CaOV3, leading to TRAIL-mediated a...

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Detalles Bibliográficos
Autores principales: Goncharenko-Khaider, N, Lane, D, Matte, I, Rancourt, C, Piché, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007125/
https://www.ncbi.nlm.nih.gov/pubmed/20661217
http://dx.doi.org/10.1038/onc.2010.288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007125/
https://www.ncbi.nlm.nih.gov/pubmed/20661217
http://dx.doi.org/10.1038/onc.2010.288

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