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Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice via S1P(1) receptor activation
Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine 1-phosphate (S1P) levels. Furthermore, exogenous sphinga...
Autores principales: | Park, Sang Won, Kim, Mihwa, Chen, Sean W. C., Brown, Kevin M., D’Agati, Vivette D., Lee, H. Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007623/ https://www.ncbi.nlm.nih.gov/pubmed/20458275 http://dx.doi.org/10.1038/labinvest.2010.102 |
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