Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1

In a previous study it was found that the therapeutic effects of QLT0267, a small molecule inhibitor of integrin-linked kinase (ILK), were influenced by Her2/neu expression. To understand how inhibition or silencing of ILK influences Her2/neu expression, Her2/neu signaling was evaluated in six Her2/...

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Detalles Bibliográficos
Autores principales: Kalra, J, Sutherland, B W, Stratford, A L, Dragowska, W, Gelmon, K A, Dedhar, S, Dunn, S E, Bally, M B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007675/
https://www.ncbi.nlm.nih.gov/pubmed/20838384
http://dx.doi.org/10.1038/onc.2010.366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007675/
https://www.ncbi.nlm.nih.gov/pubmed/20838384
http://dx.doi.org/10.1038/onc.2010.366

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