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Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1
In a previous study it was found that the therapeutic effects of QLT0267, a small molecule inhibitor of integrin-linked kinase (ILK), were influenced by Her2/neu expression. To understand how inhibition or silencing of ILK influences Her2/neu expression, Her2/neu signaling was evaluated in six Her2/...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007675/ https://www.ncbi.nlm.nih.gov/pubmed/20838384 http://dx.doi.org/10.1038/onc.2010.366 |