Molecular disruption of NBS1 with targeted gene delivery enhances chemosensitisation in head and neck cancer

BACKGROUND: A fibroblast growth factor 2 (FGF2)-targeted adenoviral system can alter viral tropism and allow for improved transduction and reduced systemic toxicity. This study is to investigate if the FGF2-targeted adenoviral mutant Nijmegen breakage syndrome 1 (FGF2-Ad-NBS1) gene transfer can enha...

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Detalles Bibliográficos
Autores principales: Araki, K, Yamashita, T, Reddy, N, Wang, H, Abuzeid, W M, Khan, K, O'Malley, B W, Li, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008607/
https://www.ncbi.nlm.nih.gov/pubmed/21063405
http://dx.doi.org/10.1038/sj.bjc.6605980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008607/
https://www.ncbi.nlm.nih.gov/pubmed/21063405
http://dx.doi.org/10.1038/sj.bjc.6605980

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