Vaccination with Ad5 Vectors Expands Ad5-Specific CD8(+) T Cells without Altering Memory Phenotype or Functionality

BACKGROUND: Adenoviral (Ad) vaccine vectors represent both a vehicle to present a novel antigen to the immune system as well as restimulation of immune responses against the Ad vector itself. To what degree Ad-specific CD8(+) T cells are restimulated by Ad vector vaccination is unclear, although suc...

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Detalles Bibliográficos
Autores principales: Hutnick, Natalie A., Carnathan, Diane G., Dubey, Sheri A., Cox, Kara S., Kierstead, Lisa, Makadonas, George, Ratcliffe, Sarah J., Lasaro, Marcio O., Robertson, Michael N., Casimiro, Danilo R., Ertl, Hildegund C. J., Betts, Michael R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008674/
https://www.ncbi.nlm.nih.gov/pubmed/21203546
http://dx.doi.org/10.1371/journal.pone.0014385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008674/
https://www.ncbi.nlm.nih.gov/pubmed/21203546
http://dx.doi.org/10.1371/journal.pone.0014385

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