Trace Levels of Innate Immune Response Modulating Impurities (IIRMIs) Synergize to Break Tolerance to Therapeutic Proteins

Therapeutic proteins such as monoclonal antibodies, replacement enzymes and toxins have significantly improved the therapeutic options for multiple diseases, including cancer and inflammatory diseases as well as enzyme deficiencies and inborn errors of metabolism. However, immune responses to these...

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Detalles Bibliográficos
Autores principales: Verthelyi, Daniela, Wang, Vivian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008684/
https://www.ncbi.nlm.nih.gov/pubmed/21203556
http://dx.doi.org/10.1371/journal.pone.0015252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008684/
https://www.ncbi.nlm.nih.gov/pubmed/21203556
http://dx.doi.org/10.1371/journal.pone.0015252

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