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Purinergic Receptor Stimulation Reduces Cytotoxic Edema and Brain Infarcts in Mouse Induced by Photothrombosis by Energizing Glial Mitochondria

Treatments to improve the neurological outcome of edema and cerebral ischemic stroke are severely limited. Here, we present the first in vivo single cell images of cortical mouse astrocytes documenting the impact of single vessel photothrombosis on cytotoxic edema and cerebral infarcts. The volume o...

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Detalles Bibliográficos
Autores principales: Zheng, Wei, Watts, Lora Talley, Holstein, Deborah M., Prajapati, Suresh I., Keller, Charles, Grass, Eileen H., Walter, Christi A., Lechleiter, James D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008710/
https://www.ncbi.nlm.nih.gov/pubmed/21203502
http://dx.doi.org/10.1371/journal.pone.0014401