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The Transcriptional Response in Human Umbilical Vein Endothelial Cells Exposed to Insulin: A Dynamic Gene Expression Approach

BACKGROUND: In diabetes chronic hyperinsulinemia contributes to the instability of the atherosclerotic plaque and stimulates cellular proliferation through the activation of the MAP kinases, which in turn regulate cellular proliferation. However, it is not known whether insulin itself could increase...

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Detalles Bibliográficos
Autores principales: Di Camillo, Barbara, Sanavia, Tiziana, Iori, Elisabetta, Bronte, Vincenzo, Roncaglia, Enrica, Maran, Alberto, Avogaro, Angelo, Toffolo, Gianna, Cobelli, Claudio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008714/
https://www.ncbi.nlm.nih.gov/pubmed/21203503
http://dx.doi.org/10.1371/journal.pone.0014390