The Batten Disease Palmitoyl Protein Thioesterase 1 Gene Regulates Neural Specification and Axon Connectivity during Drosophila Embryonic Development

Palmitoyl Protein Thioesterase 1 (PPT1) is an essential lysosomal protein in the mammalian nervous system whereby defects result in a fatal pediatric disease called Infantile Neuronal Ceroids Lipofuscinosis (INCL). Flies bearing mutations in the Drosophila ortholog Ppt1 exhibit phenotypes similar to...

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Detalles Bibliográficos
Autores principales: Chu-LaGraff, Quynh, Blanchette, Cassandra, O'Hern, Patrick, Denefrio, Cassandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008717/
https://www.ncbi.nlm.nih.gov/pubmed/21203506
http://dx.doi.org/10.1371/journal.pone.0014402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008717/
https://www.ncbi.nlm.nih.gov/pubmed/21203506
http://dx.doi.org/10.1371/journal.pone.0014402

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