Amyloid-β Inhibits No-cGMP Signaling in a CD36- and CD47-Dependent Manner

Amyloid-β interacts with two cell surface receptors, CD36 and CD47, through which the matricellular protein thrombospondin-1 inhibits soluble guanylate cyclase activation. Here we examine whether amyloid-β shares this inhibitory activity. Amyloid-β inhibited both drug and nitric oxide-mediated activ...

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Detalles Bibliográficos
Autores principales: Miller, Thomas W., Isenberg, Jeff S., Shih, Hubert B., Wang, Yichen, Roberts, David D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008726/
https://www.ncbi.nlm.nih.gov/pubmed/21203512
http://dx.doi.org/10.1371/journal.pone.0015686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008726/
https://www.ncbi.nlm.nih.gov/pubmed/21203512
http://dx.doi.org/10.1371/journal.pone.0015686

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