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Amyloid-β Inhibits No-cGMP Signaling in a CD36- and CD47-Dependent Manner
Amyloid-β interacts with two cell surface receptors, CD36 and CD47, through which the matricellular protein thrombospondin-1 inhibits soluble guanylate cyclase activation. Here we examine whether amyloid-β shares this inhibitory activity. Amyloid-β inhibited both drug and nitric oxide-mediated activ...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008726/ https://www.ncbi.nlm.nih.gov/pubmed/21203512 http://dx.doi.org/10.1371/journal.pone.0015686 |