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Simultaneous Analysis of Multiple Mycobacterium tuberculosis Knockdown Mutants In Vitro and In Vivo

Mycobacterium tuberculosis (Mtb) represents one of the most persistent bacterial threats to human health and new drugs are needed to limit its impact. Conditional knockdown mutants can help validate new drug targets, but the analysis of individual mutants is laborious and time consuming. Here, we de...

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Detalles Bibliográficos
Autores principales: Blumenthal, Antje, Trujillo, Carolina, Ehrt, Sabine, Schnappinger, Dirk
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008731/
https://www.ncbi.nlm.nih.gov/pubmed/21203517
http://dx.doi.org/10.1371/journal.pone.0015667