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Preclinical and Clinical Development of Plant-Made Virus-Like Particle Vaccine against Avian H5N1 Influenza

The recent swine H1N1 influenza outbreak demonstrated that egg-based vaccine manufacturing has an Achille's heel: its inability to provide a large number of doses quickly. Using a novel manufacturing platform based on transient expression of influenza surface glycoproteins in Nicotiana benthami...

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Detalles Bibliográficos
Autores principales: Landry, Nathalie, Ward, Brian J., Trépanier, Sonia, Montomoli, Emanuele, Dargis, Michèle, Lapini, Giulia, Vézina, Louis-P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008737/
https://www.ncbi.nlm.nih.gov/pubmed/21203523
http://dx.doi.org/10.1371/journal.pone.0015559