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Preclinical and Clinical Development of Plant-Made Virus-Like Particle Vaccine against Avian H5N1 Influenza
The recent swine H1N1 influenza outbreak demonstrated that egg-based vaccine manufacturing has an Achille's heel: its inability to provide a large number of doses quickly. Using a novel manufacturing platform based on transient expression of influenza surface glycoproteins in Nicotiana benthami...
Autores principales: | Landry, Nathalie, Ward, Brian J., Trépanier, Sonia, Montomoli, Emanuele, Dargis, Michèle, Lapini, Giulia, Vézina, Louis-P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008737/ https://www.ncbi.nlm.nih.gov/pubmed/21203523 http://dx.doi.org/10.1371/journal.pone.0015559 |
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