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Caspase-3 Is Transiently Activated without Cell Death during Early Antigen Driven Expansion of CD8(+) T Cells In Vivo

BACKGROUND: CD8(+) T cell responses develop rapidly during infection and are swiftly reduced during contraction, wherein >90% of primed CD8(+) T cells are eliminated. The role of apoptotic mechanisms in controlling this rapid proliferation and contraction of CD8(+) T cells remains unclear. Surpri...

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Detalles Bibliográficos
Autores principales: McComb, Scott, Mulligan, Rebecca, Sad, Subash
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008739/
https://www.ncbi.nlm.nih.gov/pubmed/21203525
http://dx.doi.org/10.1371/journal.pone.0015328