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Caspase-3 Is Transiently Activated without Cell Death during Early Antigen Driven Expansion of CD8(+) T Cells In Vivo
BACKGROUND: CD8(+) T cell responses develop rapidly during infection and are swiftly reduced during contraction, wherein >90% of primed CD8(+) T cells are eliminated. The role of apoptotic mechanisms in controlling this rapid proliferation and contraction of CD8(+) T cells remains unclear. Surpri...
Autores principales: | McComb, Scott, Mulligan, Rebecca, Sad, Subash |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008739/ https://www.ncbi.nlm.nih.gov/pubmed/21203525 http://dx.doi.org/10.1371/journal.pone.0015328 |
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