JAMM: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome

The JAMM (JAB1/MPN/Mov34 metalloenzyme) motif in Rpn11 and Csn5 underlies isopeptidase activities intrinsic to the proteasome and signalosome, respectively. We show here that the archaebacterial protein AfJAMM possesses the key features of a zinc metalloprotease, yet with a distinct fold. The histid...

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Detalles Bibliográficos
Autores principales: Ambroggio, Xavier I, Rees, Douglas C, Deshaies, Raymond J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300881/
https://www.ncbi.nlm.nih.gov/pubmed/14737182
http://dx.doi.org/10.1371/journal.pbio.0020002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC300881/
https://www.ncbi.nlm.nih.gov/pubmed/14737182
http://dx.doi.org/10.1371/journal.pbio.0020002

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