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Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis

BACKGROUND: An explosive global spreading of multidrug resistant Mycobacterium tuberculosis (Mtb) is a catastrophe, which demands an urgent need to design or develop novel/potent antitubercular agents. The Lysine/DAP biosynthetic pathway is a promising target due its specific role in cell wall and a...

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Detalles Bibliográficos
Autores principales: Garg, Aarti, Tewari, Rupinder, Raghava, Gajendra PS
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009526/
https://www.ncbi.nlm.nih.gov/pubmed/20122228
http://dx.doi.org/10.1186/1471-2105-11-S1-S53