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Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2

BACKGROUND: Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rather than the secondary structure, is believed to be the major factor defining the antimicrobial activity of defensins. To...

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Detalles Bibliográficos
Autores principales: Soman, Soja Saghar, Sivakumar, Krishnankutty Chandrika, Sreekumar, Easwaran
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009542/
https://www.ncbi.nlm.nih.gov/pubmed/20122244
http://dx.doi.org/10.1186/1471-2105-11-S1-S7