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Physical determinants of strong voltage sensitivity of K(+) channel block
Strong voltage sensitivity of inward-rectifier K(+) (Kir) channels has been hypothesized to arise primarily from an intracellular blocker displacing up to five K(+) ions from the wide, intracellular part of the ion conduction pore outwardly across the narrow ion selectivity filter. The validity of t...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009588/ https://www.ncbi.nlm.nih.gov/pubmed/19915587 http://dx.doi.org/10.1038/nsmb.1717 |