Hypoxia Induces an Immunodominant Target of Tuberculosis Specific T Cells Absent from Common BCG Vaccines

M. tuberculosis (MTB) species-specific antigenic determinants of the human T cell response are important for immunodiagnosis and vaccination. As hypoxia is a stimulus in chronic tuberculosis infection, we analyzed transcriptional profiles of MTB subject to 168 hours of hypoxia to test the hypothesis...

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Detalles Bibliográficos
Autores principales: Gideon, Hannah Priyadarshini, Wilkinson, Katalin Andrea, Rustad, Tige R., Oni, Tolu, Guio, Heinner, Kozak, Robert Andrew, Sherman, David R., Meintjes, Graeme, Behr, Marcel A., Vordermeier, Hans Martin, Young, Douglas Brownlee, Wilkinson, Robert John
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009603/
https://www.ncbi.nlm.nih.gov/pubmed/21203487
http://dx.doi.org/10.1371/journal.ppat.1001237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009603/
https://www.ncbi.nlm.nih.gov/pubmed/21203487
http://dx.doi.org/10.1371/journal.ppat.1001237

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