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The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac

BACKGROUND: RhoGDI proteins are important regulators of the small GTPase Rac, because they shuttle Rac from the cytoplasm to membranes and also protect Rac from activation, deactivation and degradation. How the binding and release of Rac from RhoGDI is regulated is not precisely understood. RESULTS:...

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Detalles Bibliográficos
Autores principales: Fei, Fei, Kweon, Soo-Mi, Haataja, Leena, De Sepulveda, Paulo, Groffen, John, Heisterkamp, Nora
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009610/
https://www.ncbi.nlm.nih.gov/pubmed/21122136
http://dx.doi.org/10.1186/1471-2091-11-48