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Inflammatory responses in epithelia: endotoxin-induced IL-6 secretion and iNOS/NO production are differentially regulated in mouse mammary epithelial cells

BACKGROUND: IL-6 is a pro-inflammatory cytokine that signals via binding to a soluble or membrane bound receptor, while nitric oxide (NO), an oxidative stress molecule, diffuses through the cell membrane without a receptor. Both mediators signal through different mechanisms, yet they are dependent o...

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Detalles Bibliográficos
Autores principales: Maalouf, Samar W, Talhouk, Rabih S, Schanbacher, Floyd L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009620/
https://www.ncbi.nlm.nih.gov/pubmed/21118556
http://dx.doi.org/10.1186/1476-9255-7-58