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Enhancement of antinociception by coadminstration of minocycline and a non-steroidal anti-inflammatory drug indomethacin in naïve mice and murine models of LPS-induced thermal hyperalgesia and monoarthritis

BACKGROUND: Minocycline and a non-steroidal anti-inflammatory drug (NSAID) indomethacin, have anti-inflammatory activities and are both used in the management of rheumatoid arthritis. However, there are no reports on whether coadministration of these drugs could potentiate each other's activiti...

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Detalles Bibliográficos
Autores principales: Abu-Ghefreh, Ala'a Ahmed, Masocha, Willias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009629/
https://www.ncbi.nlm.nih.gov/pubmed/21122103
http://dx.doi.org/10.1186/1471-2474-11-276