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A Role for ATF2 in Regulating MITF and Melanoma Development
The transcription factor ATF2 has been shown to attenuate melanoma susceptibility to apoptosis and to promote its ability to form tumors in xenograft models. To directly assess ATF2's role in melanoma development, we crossed a mouse melanoma model (Nras(Q61K)::Ink4a(−/−)) with mice expressing a...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009656/ https://www.ncbi.nlm.nih.gov/pubmed/21203491 http://dx.doi.org/10.1371/journal.pgen.1001258 |