A Role for ATF2 in Regulating MITF and Melanoma Development

The transcription factor ATF2 has been shown to attenuate melanoma susceptibility to apoptosis and to promote its ability to form tumors in xenograft models. To directly assess ATF2's role in melanoma development, we crossed a mouse melanoma model (Nras(Q61K)::Ink4a(−/−)) with mice expressing a...

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Detalles Bibliográficos
Autores principales: Shah, Meera, Bhoumik, Anindita, Goel, Vikas, Dewing, Antimone, Breitwieser, Wolfgang, Kluger, Harriet, Krajewski, Stan, Krajewska, Maryla, DeHart, Jason, Lau, Eric, Kallenberg, David M., Jeong, Hyeongnam, Eroshkin, Alexey, Bennett, Dorothy C., Chin, Lynda, Bosenberg, Marcus, Jones, Nic, Ronai, Ze'ev A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009656/
https://www.ncbi.nlm.nih.gov/pubmed/21203491
http://dx.doi.org/10.1371/journal.pgen.1001258

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