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Season of Conception in Rural Gambia Affects DNA Methylation at Putative Human Metastable Epialleles

Throughout most of the mammalian genome, genetically regulated developmental programming establishes diverse yet predictable epigenetic states across differentiated cells and tissues. At metastable epialleles (MEs), conversely, epigenotype is established stochastically in the early embryo then maint...

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Detalles Bibliográficos
Autores principales: Waterland, Robert A., Kellermayer, Richard, Laritsky, Eleonora, Rayco-Solon, Pura, Harris, R. Alan, Travisano, Michael, Zhang, Wenjuan, Torskaya, Maria S., Zhang, Jiexin, Shen, Lanlan, Manary, Mark J., Prentice, Andrew M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009670/
https://www.ncbi.nlm.nih.gov/pubmed/21203497
http://dx.doi.org/10.1371/journal.pgen.1001252