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Initiator Elements Function to Determine the Activity State of BX-C Enhancers

A >300 kb cis-regulatory region is required for the proper expression of the three bithorax complex (BX-C) homeotic genes. Based on genetic and transgenic analysis, a model has been proposed in which the numerous BX-C cis-regulatory elements are spatially restricted through the activation or repr...

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Detalles Bibliográficos
Autores principales: Iampietro, Carole, Gummalla, Maheshwar, Mutero, Annick, Karch, François, Maeda, Robert K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009686/
https://www.ncbi.nlm.nih.gov/pubmed/21203501
http://dx.doi.org/10.1371/journal.pgen.1001260