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Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation

BACKGROUND: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gene expression. The analysis of such changes is complicated, as they consist of multi-layered temporal responses. While cla...

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Detalles Bibliográficos
Autores principales: Kowarsch, Andreas, Blöchl, Florian, Bohl, Sebastian, Saile, Maria, Gretz, Norbert, Klingmüller, Ursula, Theis, Fabian J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009690/
https://www.ncbi.nlm.nih.gov/pubmed/21118515
http://dx.doi.org/10.1186/1471-2105-11-585