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Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
BACKGROUND: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gene expression. The analysis of such changes is complicated, as they consist of multi-layered temporal responses. While cla...
Autores principales: | Kowarsch, Andreas, Blöchl, Florian, Bohl, Sebastian, Saile, Maria, Gretz, Norbert, Klingmüller, Ursula, Theis, Fabian J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009690/ https://www.ncbi.nlm.nih.gov/pubmed/21118515 http://dx.doi.org/10.1186/1471-2105-11-585 |
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