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Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism

Deep sequencing is able to generate a complete picture of the retroviral quasi-species in a patient. We demonstrate that the unprecedented power of deep sequencing in conjunction with computational data analysis has great potential for clinical diagnostics and basic research. Specifically, we analyz...

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Detalles Bibliográficos
Autores principales: Dybowski, J Nikolaj, Heider, Dominik, Hoffmann, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009693/
https://www.ncbi.nlm.nih.gov/pubmed/21118549
http://dx.doi.org/10.1186/1742-6405-7-41