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Critical Role of Macrophages and Their Activation via MyD88-NFκB Signaling in Lung Innate Immunity to Mycoplasma pneumoniae

Mycoplasma pneumoniae (Mp), a common cause of pneumonia, is associated with asthma; however, the mechanisms underlying this association remain unclear. We investigated the cellular immune response to Mp in mice. Intranasal inoculation with Mp elicited infiltration of the lungs with neutrophils, mono...

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Detalles Bibliográficos
Autores principales: Lai, Jen-Feng, Zindl, Carlene L., Duffy, Lynn B., Atkinson, T. Prescott, Jung, Yong Woo, van Rooijen, Nico, Waites, Ken B., Krause, Duncan C., Chaplin, David D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009709/
https://www.ncbi.nlm.nih.gov/pubmed/21203444
http://dx.doi.org/10.1371/journal.pone.0014417