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Tumour Cannabinoid CB(1) Receptor and Phosphorylated Epidermal Growth Factor Receptor Expression Are Additive Prognostic Markers for Prostate Cancer

BACKGROUND: In cultured prostate cancer cells, down-regulation of epidermal growth factor receptor (EGFR) has been implicated in mediating the antiproliferative effect of the endogenous cannabinoid (CB) ligand anandamide. Using a well-characterised cohort of prostate cancer patients, we have previou...

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Detalles Bibliográficos
Autores principales: Fowler, Christopher J., Hammarsten, Peter, Bergh, Anders
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009725/
https://www.ncbi.nlm.nih.gov/pubmed/21203460
http://dx.doi.org/10.1371/journal.pone.0015205