Pharmacological Evaluation of the Long-Term Effects of Xanomeline on the M(1) Muscarinic Acetylcholine Receptor

Xanomeline is a unique agonist of muscarinic receptors that possesses functional selectivity at the M(1) and M(4) receptor subtypes. It also exhibits wash-resistant binding to and activation of the receptor. In the present work we investigated the consequences of this type of binding of xanomeline o...

Descripción completa

Detalles Bibliográficos
Autores principales: Grant, Marianne K. O., Noetzel, Meredith J., De Lorme, Kayla C., Jakubík, Jan, Doležal, Vladimír, El-Fakahany, Esam E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009740/
https://www.ncbi.nlm.nih.gov/pubmed/21203415
http://dx.doi.org/10.1371/journal.pone.0015722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009740/
https://www.ncbi.nlm.nih.gov/pubmed/21203415
http://dx.doi.org/10.1371/journal.pone.0015722

Ejemplares similares