In Vivo Imaging of HIF-Active Tumors by an Oxygen-Dependent Degradation Protein Probe with an Interchangeable Labeling System

Hypoxia-inducible factor (HIF) functions as a master transcriptional regulator for adaptation to hypoxia by inducing adaptive changes in gene expression for regulation of proliferation, angiogenesis, apoptosis and energy metabolism. Cancers with high expression of the alpha subunit of HIF (HIFα) are...

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Detalles Bibliográficos
Autores principales: Kuchimaru, Takahiro, Kadonosono, Tetsuya, Tanaka, Shotaro, Ushiki, Takashi, Hiraoka, Masahiro, Kizaka-Kondoh, Shinae
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009742/
https://www.ncbi.nlm.nih.gov/pubmed/21203417
http://dx.doi.org/10.1371/journal.pone.0015736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009742/
https://www.ncbi.nlm.nih.gov/pubmed/21203417
http://dx.doi.org/10.1371/journal.pone.0015736

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