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An Intact Centrosome Is Required for the Maintenance of Polarization during Directional Cell Migration

BACKGROUND: Establishing and maintaining polarization is critical during cell migration. It is known that the centrosome contains numerous proteins whose roles of organizing the microtubule network range include nucleation, stabilization and severing. It is not known whether the centrosome is necess...

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Detalles Bibliográficos
Autores principales: Wakida, Nicole M., Botvinick, Elliot L., Lin, Justin, Berns, Michael W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009746/
https://www.ncbi.nlm.nih.gov/pubmed/21203421
http://dx.doi.org/10.1371/journal.pone.0015462