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Two novel human NUMB isoforms provide a potential link between development and cancer

We previously identified four functionally distinct human NUMB isoforms. Here, we report the identification of two additional isoforms and propose a link between the expression of these isoforms and cancer. These novel isoforms, NUMB5 and NUMB6, lack exon 10 and are expressed in cells known for pola...

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Detalles Bibliográficos
Autores principales: Karaczyn, Aldona, Bani-Yaghoub, Mahmud, Tremblay, Roger, Kubu, Chris, Cowling, Rebecca, Adams, Tamara L, Prudovsky, Igor, Spicer, Douglas, Friesel, Robert, Vary, Calvin, Verdi, Joseph M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009962/
https://www.ncbi.nlm.nih.gov/pubmed/21122105
http://dx.doi.org/10.1186/1749-8104-5-31