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Culling sick mitochondria from the herd
The PINK1–Parkin pathway plays a critical role in mitochondrial quality control by selectively targeting damaged mitochondria for autophagy. In this issue, Tanaka et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201007013) demonstrate that the AAA-type ATPase p97 acts downstream of PINK1 and Parkin to s...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010062/ https://www.ncbi.nlm.nih.gov/pubmed/21187326 http://dx.doi.org/10.1083/jcb.201011068 |