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Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice

Skeletal muscle wasting is a major human morbidity, and contributes to mortality in a variety of clinical settings, including denervation and cancer cachexia. In this study, we demonstrate that the expression level and autoubiquitination of tumor necrosis factor (α) receptor adaptor protein 6 (TRAF6...

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Detalles Bibliográficos
Autores principales: Paul, Pradyut K., Gupta, Sanjay K., Bhatnagar, Shephali, Panguluri, Siva K., Darnay, Bryant G., Choi, Yongwon, Kumar, Ashok
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010064/
https://www.ncbi.nlm.nih.gov/pubmed/21187332
http://dx.doi.org/10.1083/jcb.201006098