Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

Damage to mitochondria can lead to the depolarization of the inner mitochondrial membrane, thereby sensitizing impaired mitochondria for selective elimination by autophagy. However, fusion of uncoupled mitochondria with polarized mitochondria can compensate for damage, reverse membrane depolarizatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanaka, Atsushi, Cleland, Megan M., Xu, Shan, Narendra, Derek P., Suen, Der-Fen, Karbowski, Mariusz, Youle, Richard J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010068/
https://www.ncbi.nlm.nih.gov/pubmed/21173115
http://dx.doi.org/10.1083/jcb.201007013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010068/
https://www.ncbi.nlm.nih.gov/pubmed/21173115
http://dx.doi.org/10.1083/jcb.201007013

Ejemplares similares