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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
Damage to mitochondria can lead to the depolarization of the inner mitochondrial membrane, thereby sensitizing impaired mitochondria for selective elimination by autophagy. However, fusion of uncoupled mitochondria with polarized mitochondria can compensate for damage, reverse membrane depolarizatio...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010068/ https://www.ncbi.nlm.nih.gov/pubmed/21173115 http://dx.doi.org/10.1083/jcb.201007013 |