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A computational model predicts Xenopus meiotic spindle organization

The metaphase spindle is a dynamic bipolar structure crucial for proper chromosome segregation, but how microtubules (MTs) are organized within the bipolar architecture remains controversial. To explore MT organization along the pole-to-pole axis, we simulated meiotic spindle assembly in two dimensi...

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Detalles Bibliográficos
Autores principales: Loughlin, Rose, Heald, Rebecca, Nédélec, François
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010074/
https://www.ncbi.nlm.nih.gov/pubmed/21173114
http://dx.doi.org/10.1083/jcb.201006076